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Year : 2014  |  Volume : 4  |  Issue : 1  |  Page : 31-34

Recent advances in the management of Plasmodium knowlesi infection

Department of Medicine, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry, India

Correspondence Address:
T K Dutta
Senior Professor, Department of General Medicine, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry 605 006
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2229-5070.129158

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Plasmodium knowlesi (P. knowlesi) has been detected to be the fifth malarial parasite that can cause malaria in human beings. The parasite is known to commonly infect macaque monkeys. The infection is highly prevalent in South-East Asia. It has morphologic similarities to Plasmodium malariae and Plasmodium falciparum. P. knowlesi is known to replicate every 24 h in the human host and hence, causes "quotidian malaria." It causes a wide spectrum of clinical manifestations and sometimes can cause fatal illness. Chloroquine is effective in the treatment of uncomplicated P. knowlesi infection. Severe and complicated P. knowlesi malaria can be managed with artemisinin combination therapy.

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