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Year : 2014  |  Volume : 4  |  Issue : 2  |  Page : 111-114

Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica

1 Department of Pathology and Infectious Diseases, Royal Veterinary College, University of London, Hatfield, United Kingdom
2 Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium; Barcelona Centre for International Health Research (CRESIB, Hospital Clínic Universitat de Barcelona), Barcelona, Spain
3 Faculty of Microbiology, Centre for Research in Tropical Diseases (CIET), University of Costa Rica, San José, Costa Rica
4 School of Veterinary Medicine, Universidad Nacional, Heredia, Costa Rica

Correspondence Address:
Albert Picado
Barcelona Centre for International Health Research (CRESIB, Hospital Clínic-Universitat de Barcelona), Roselló 132, 4th Floor (08036), Barcelona, Spain

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Source of Support: Royal Society (International Travel Grants - 2010/R3). S. Deborggraeve is a postdoctoral fellow of the Research Foundation Flanders (FWO)., Conflict of Interest: None

DOI: 10.4103/2229-5070.138539

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Introduction: Chagas disease is a zoonotic disease caused by Trypanosoma cruzi and dogs are one of the main domestic reservoirs. Materials and Methods: One molecular (OligoC-TesT, Coris Bioconcept) and one serological (T. cruzi-Detect, Inbios) rapid tests were evaluated as infection markers for T. cruzi in 102 dogs living in eight villages endemic for Chagas in Costa Rica. Results: T. cruzi-Detect performed well as screening tool with 23.3% positive samples. The large number of invalid results (66.7%) observed in samples tested with OligoC-TesT precluded assessing the use of this new method as epidemiological tool to detect T. cruzi infection in dogs.

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